The First “Holter” for Parkinson’s Disease

A sensor gathers information on the patient's motor symptoms at all times, with an effectiveness rate of 87% in identifying the presence of motor skills and of 100% in identifying the lack thereof.

The first “holter” for Parkinson’s. Click for more information

The Universitat Politècnica de Catalunya (UPC), the Quirón Teknon hospital and Telefónica, who manage the European REMPARK telemedicine project, showcased the crucial role that the first “holter” for Parkinson’s has played in their research on this disease, labelling the device as “revolutionary” in its capabilities to open up new fields in the diagnosis, treatment and management of Parkinson’s Disease (PD).

Joan Cabestany—a professor at the UPC and  a researcher for the Centre for Technological Studies for the Care of Dependant people and promotion of Autonomous Living (abbreviated as CETpD, in Spanish), the institution that coordinates the project—, Angels Bayés—the director of the Parkinson’s Unit at the Quirón Teknon hospital in Barcelona—and Jaume Raventós, Telefónica Spain’s eHealth director, presented their first conclusions on the European project today. For the last three years the project has been studying the evolution of 40 Parkinson’s patients in Spain, Italy, Ireland and Israel using a remote control and tele-monitoring system running on Telefónica’s remote management platform.

The main goal driving REMPARK has been to accurately determine and quantify symptoms connected to the motor system in order to monitor their evolution. Having achieved this goal, it is now possible to replace the typical journal that Parkinson’s patients fill out with an entirely automatic system. The importance of this improvement lies in the fact that, due to the fluctuations patients experience, their motor state is not constant throughout the day—in some cases, they experience dramatic changes—, which makes it nearly impossible for them to accurately register said information.

Given that the treatment of PD is symptomatic, detailed knowledge of patients’ motor state is fundamental to optimise their treatment and improve their quality of life. This gives patients the possibility to self-manage their disease more easily, and affords physicians the chance to adapt and personalise each patient’s treatment.

The REMPARK system is essentially made up of a device the size of a mobile phone which the patient wears around their waist, attached to a bio-compatible waist-band. This device measures, processes and transmits all information connected to motor symptoms experienced by the patient. Inside the device there are a series of sensors, a microprocessor and a Bluetooth interface which allows it to communicate with a Smartphone. Nonetheless, the most important elements are the algorithms that have been developed for the device.

The system detects symptomatological parameters associated with the disease and determines the phase the patient is in at all times (on-off states, dyskinesia, freezing of gait, bradykinesia) and sends this information to the patient’s doctor via a remote management system. The doctor can then remotely and accurately follow up with the patient where necessary and adjust their medication without having to wait until the next consultation.

The REMPARK system has a central server where all data sent by the device is securely and responsibly stored, processed and analysed in order to track long-term evolution as well as significant patterns and trends. It also serves as an intelligent backup system, assisting the supervising team of physicians in making decisions. The sensor has proven to be 87% accurate in correctly identifying the presence of motor skills, and to have 100% success in correctly identifying the lack of motor skills when these are not present.

The project’s managers have confirmed that this device, which uses exclusive algorithms, is a foundation on which to make further advances relating to this disease. Just as people suffering from hypertension have blood pressure monitors at home to monitor their arterial tension, people suffering from Parkinson’s disease will soon be able to purchase a PD holter to self-manage their disease, particularly during its first stages.

Joan Cabestany, a professor at the UPC, explained that “The doctors participating in this project believe Rempark to be a big step forward in managing Parkinson’s disease. We intend to keep investing and working on the sensor so that we can release it commercially as soon as possible and ensure that it’s compatible with EU regulations on primary healthcare devices. We know what we’ve got to do to succeed. This is a very possible scenario, depending on funds and extended pilot testing.”

Telefónica is working to integrate their remote management services into healthcare systems, which would bring about considerable medical, social and economic benefits, as it would increase patients’ level of independence, improve disease management and even prevent hospital admissions caused by the inappropriate administration of medication, as this could be dosed according to the patient’s state.

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