Shiseido Discovers Involvement of Vascular Plexus Malformation in Hyperpigmentation

Shiseido has been long engaging in skin analysis with a focus on skin reaction specifically seen in pigmented skin and clarifying various causes of hyperpigmentation. This time, Shiseido has pursued research on the relationship between hyperpigmentation and vascular morphology, and discovered the involvement of vascular plexus malformation in hyperpigmentation.

Moreover, Shiseido elucidated that the activity of vascular endothelial cells partly causes hyperpigmentation and uneven complexion in a joint research with Dr. Kang of Department of Dermatology, Ajou University School of Medicine, South Korea. Shiseido has also found out that Tormentilla extract and Pyrola incarnata extract have an inhibitory effect on the abnormal reaction of vasculature, which is associated with the development of hyperpigmentation.